Barcelona's preparations for next season were thrown off course on Friday when the Spanish champions unexpectedly announced coach Tito Vilanova was stepping down due to ill health.
According to widespread Spanish media reports, Netherlands coach and former Barca defender Ronald Koeman is set to be named as Setien's successor.
Spanish La Liga champions Barcelona were in turmoil on Friday after six board directors resigned criticising the clubs's handling of a social media scandal and the financial implications of the coronavirus crisis. Two of the club's four vice presidents, Emili Rousaud and Enrique Tombas, were among those to quit, joined by directors Silvio Elias, Josep Pont, Jordi Calsamiglia and Maria Texidor.
The referee who awarded Real Madrid the stoppage-time penalty that secured a 2-1 La Liga win at Elche on Wednesday may not have been in the right state of mind to take charge of the game, the head of Spain's referees' committee said on Thursday.
Barcelona's payment of 40 million euros to a company owned by Neymar's father as part of the Brazil forward's 57.1 million euros transfer fee is being investigated by Spanish state prosecutors for misappropriation of funds.
Neymar took time to settle but is finally shining in Barcelona's devastating attacking trident with Villarreal the next La Liga opponents in their sights on Sunday as the Catalans continue their pursuit of Real Madrid.
Barcelona are still trying to lure Paris St Germain centre back Thiago Silva to the Nou Camp but will look elsewhere if they fail to snare the Brazil international, coach Tito Vilanova said on Tuesday.
Barcelona coach Luis Enrique is head strong but it appears as though he may be fighting a losing battle with the four times World Player of the Year.
'We are going through difficult and complicated moments and with respect to what could happen in the future we will take it on with calm and wisdom'
Setien's complaint piled yet more pressure on president Josep Maria Bartomeu less than an hour after a group seeking his removal announced they had gathered enough signatures to force a vote of no-confidence against him.
Barcelona would not be allowed to play in La Liga if Catalonia broke away from Spain, the country's football league chief Javier Tebas said as tensions mounted in the region over the possibility of an independence referendum next month.
Barcelona and Brazil striker Neymar has launched an attack on his former club Santos and spoken out in support of his father, insisting he had the right to make millions from the player's transfer last year.